Fatty Liver disease or MASLD or MASH (formerly known as NAFLD or non-alcoholic fatty liver disease) is a very common form of liver disease. Up to one in three individuals are estimated to have this condition in North America and its prevalence is increasing worldwide.
As the name suggests, this liver disease is primarily caused by the buildup of fat in the liver. Over time, excess fat can lead to liver inflammation, scarring (fibrosis), and potentially serious liver damage.
The main risk factors for fat accumulation in the liver include:
An inactive lifestyle and poor diet
Obesity
High cholesterol or triglycerides
Type 2 diabetes or insulin resistance
High blood pressure (hypertension)
These factors often cluster together as part of a condition called metabolic syndrome, which significantly increases the risk of developing fatty liver disease.
The most common way we first detect that the liver may not be healthy is through routine blood tests that check liver enzymes. These tests can show early signs of liver stress, even before symptoms appear, so regular testing is important!
If the blood tests suggest a problem, the next step is often a shearwave liver ultrasound. This imaging test gives us a look at the liver, identify signs of fat buildup and assess for liver scarring. If fat is seen in the liver, and other causes are ruled out, we can diagnose fatty liver disease, ideally early enough to take steps to reverse the damage.
There’s no quick fix for fatty liver disease, but the good news is that if liver damage hasn’t progressed to severe scarring (cirrhosis), it can often be reversed. Treatment focuses on addressing the underlying causes and gradually reducing the amount of fat in the liver.
We support patients in making sustainable lifestyle changes, including:
Eating a healthier diet (check out our "Diet and Liver Health" page for ideas!)
Increasing Physical activity (aim for at least 30 minutes of moderate exercise; 5 days a week - start gradually)
Managing conditions like diabetes, high blood pressure, and high cholesterol
Quitting smoking
Limiting alcohol (alcohol adds unnecessary calories and is a toxin to the liver)
In some cases, medications may help and there are new emerging therapies for this condition! The liver specialist can help you navigate these options.
When it comes to fatty liver disease, prevention really matters. The good news is that it’s one of the most preventable chronic conditions we face today. Preventing fatty liver is much like treating it, it just starts earlier, before any damage occurs.
Here’s how you can protect your liver:
Adopt a healthy, balanced diet (Visit our “Diet and Liver Health” page for ideas!)
Stay physically active (aim for 30 minutes of activity, 5 times per week)
Limit alcohol and avoid smoking (Both can place unnecessary stress on the liver)
Maintain a healthy weight and manage conditions like diabetes, high blood pressure, or high cholesterol
And an interesting bonus, coffee has been shown in many studies to support liver health. So if you’re choosing between coffee and alcohol, your liver will thank you for picking coffee.
Fatty liver disease is increasingly common, but it’s also highly preventable. Small, steady changes in your daily routine can make a big difference in keeping your liver healthy.
Alberta Health Services has an excellent primary care pathway for Non-Alcoholic Fatty Liver Disease
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